Independent Research

  1. Coming soon!

Prior Research (NCBI profile)

  1. Woo, C. M.; Felix, A.; Byrd, W.; Zuegel, D.; Ishihara, M.; Azadi, P.; Iavarone, A. T.; Pitteri, S. J.; Bertozzi, C. R. “Development of IsoTaG, a Chemical Glycoproteomics Technique for Profiling Intact N- and O‑Glycopeptides from Whole Cell Proteomes.” J. Prot. Res. 2017, 16, 1706.
  2. Woo, C. M.; Felix, A.; Zhang, L.; Elias, J. E.; Bertozzi, C. R. “Isotope targeted glycoproteomics (IsoTaG) analysis of sialylated N- and O-glycopeptides on an Orbitrap Fusion Tribrid using azido and alkynyl sugars.” Anal. Bioanal. Chem. 2017, 409, 579.
  3. Sheta, R.; Woo, C. M.; Roux-Dalvai, F.; Fournier, F.; Bourassa, S.; Droit, A.; Bertozzi, C. R.; Bachvarov, D. “A metabolic labeling approach for glycoproteomic analysis reveals altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells.” J. Prot. 2016, 145, 91.
  4. Sheta, R.; Roux-Dalvai, F.; Woo, C. M.; Fournier, F.; Bourassa, S.; Bertozzi, C. R.; Droit, A.; Bachvarov, D. “Proteomic dataset for altered glycoprotein expression upon GALNT3 knockdown in ovarian cancer cells” Data in Brief 2016, 8, 59.
  5. Woo, C. M.; Li, Z.; Paulson, E.; Herzon, S. B. “Structural Basis for DNA Cleavage by the Potent Antiproliferative Agent (–)-Lomaiviticin A.”  Proc. Natl. Acad. Sci.  201611, 2851.
  6. Woo, C. M.; Bertozzi, C. R. “Isotope Recoding for Intact Glycoproteomics”  Curr. Protocols Chem. Bio.  2016, 8, 59.
  7. Woo, C. M.; Iavarone, A. T.; Spiciarich, D. R.; Palaniappan, K. K.; Bertozzi, C. R. “Isotope Targeted Glycoproteomics (IsoTaG): A Mass Independent Platform for Intact N- and O-Glycopeptide Discovery”  Nat. Meth. 2015,  12, 561.
  8. Woo, C. M.; Ranjan, N.; Arya, D. P.; Herzon, S. B. “Analysis of Diazofluorene DNA Binding and Damaging Activity. DNA Cleavage by a Synthetic Monomeric Diazofluorene.” Angew. Chem. Int. Ed. 2014, 53, 9325.
  9. Colis, L. C.; Woo, C. M.; Hegan, D. C.; Li, Z.; Glazer, P. M.; Herzon, S. B. “The Cytotoxicity of (–)-Lomaiviticin A Arises from Induction of Double-strand Breaks in DNA.” Nat. Chem. 20146, 504.
  10. Woo, C. M.; Gholap, S. L.; Herzon, S. B. “Insights into Lomaiviticin Biosynthesis. Isolation and Structure Elucidation of (–)-Homoseongomycin.” J. Nat. Prod. 201376, 1238.
  11. Woo, C. M.; Gholap, S. L.; Lu, L.; Kaneko, M.; Li, Z.; Ravikumar, P. C.; Herzon, S. B. “Development of Enantioselective Synthetic Routes to (–)-Kinamycin F and (–)-Lomaiviticin Aglycon.” J. Am. Chem. Soc. 2012134, 17262.
  12. Woo, C. M.; Beizer, N. E.; Janso, J. E.; Herzon, S. B. “Isolation of Lomaiviticins C–E. Transformation of Lomaiviticin C to Lomaiviticin A, Complete Structure Elucidation of Lomaiviticin A, and Structure–Activity Analyses.” J. Am. Chem. Soc. 2012134, 15285.
  13. Mulcahy, S. P.; Woo, C. M.; Ding, W.; Ellestad, G. A.; Herzon, S. B. “Characterization of a Reductively-Activated Elimination Pathway Relevant to the Biological Chemistry of the KInamycins and Lomaiviticins.” Chem. Sci. 20123, 1070.
  14. Herzon, S. B.; Woo, C. M. “The Diazofluorene Antitumor Antibiotics: Structural Elucidation, Biosynthetic, Synthetic, and Chemical Biological Studies.” Nat. Prod. Rep. 2012, 29, 87.
  15. Herzon, S. B.; Lu, L.*; Woo, C. M.*; Gholap, S. L. “11-Step Enantioselective Synthesis of (–)-Lomaiviticin Aglycon.” J. Am. Chem. Soc. 2011133, 7260. *Authors contributed equally.
  16. Woo, C. M.; Lu, L.; Gholap, S. L.; Smith, D. R.; Herzon, S. B. “Development of a Convergent Entry to the Diazofluorene Antitumor Antibiotics: Enantioselective Synthesis of Kinamycin F.” J. Am. Chem. Soc. 2010132, 2540.
  17. Gholap, S. L.; Woo, C. M.; Ravikumar, P. C.; Herzon, S. B. “Synthesis of the Fully Glycosylated Cyclohexenone Core of Lomaiviticin A.” Org. Lett. 200911, 4322.
  18. Devji, T.; Reddy, C.; Woo, C. M.; Awale, S.; Kadota, S.; Carrico-Moniz, D. “Pancreatic Anticancer Activity of a Novel Geranylgeranylated Coumarin Derivative.” Bioorg. Med. Chem. Lett. 201121, 5770.
  19. Boonya-udtayan, S.; Yotapan, N.; Woo, C. M.; Bruns, C. J.; Ruchirawat, S.; Thasana, N. “Synthesis and biological activities of azalamellarins.” Chem. Asian. J. 20105, 2113.
  20. Loehlin, J. H.; Lee, M; Woo, C. M. “Diol Symmetry, Hydrogen Bond Patterns and the Structures of 1,4-Cyclohexanediol.” Acta Cryst. 2008, B64, 583.

Manuscripts in progress

  1. Woo, C. M*.; Lund, P. J.*; Huang, A. C.; Davis, M. M.; Bertozzi, C. R.; Pitteri, S. J. “Mapping and quantification of over 2,000 O-GlcNAzylated peptides in activated human T cells with isotope-targeted glycoproteomics (IsoTaG).” 2017manuscript under review. *Authors contributed equally.